Detalhe da pesquisa
1.
Synthetic lethality-mediated precision oncology via the tumor transcriptome.
Cell
; 184(9): 2487-2502.e13, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33857424
2.
Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis.
Cell
; 184(8): 2033-2052.e21, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33765443
3.
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.
Cell
; 174(6): 1559-1570.e22, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30100185
4.
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αß T Cell Development.
Immunity
; 53(6): 1182-1201.e8, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242395
5.
A transcription-centric model of SNP-age interaction.
PLoS Genet
; 17(3): e1009427, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33770080
6.
Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.
PLoS Genet
; 17(2): e1009354, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33591981
7.
Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients.
J Transl Med
; 21(1): 209, 2023 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36941605
8.
Ligand dependent gene regulation by transient ERα clustered enhancers.
PLoS Genet
; 16(1): e1008516, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31905229
9.
PathExt: a general framework for path-based mining of omics-integrated biological networks.
Bioinformatics
; 37(9): 1254-1262, 2021 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305329
10.
Prioritizing and characterizing functionally relevant genes across human tissues.
PLoS Comput Biol
; 17(7): e1009194, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270548
11.
Distal CpG islands can serve as alternative promoters to transcribe genes with silenced proximal promoters.
Genome Res
; 27(4): 553-566, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223400
12.
Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy.
Mol Syst Biol
; 15(3): e8323, 2019 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858180
13.
ChIPulate: A comprehensive ChIP-seq simulation pipeline.
PLoS Comput Biol
; 15(3): e1006921, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30897079
14.
Heterogeneity of transcription factor binding specificity models within and across cell lines.
Genome Res
; 26(8): 1110-23, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27311443
15.
Analysis and correction of compositional bias in sparse sequencing count data.
BMC Genomics
; 19(1): 799, 2018 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30400812
16.
Correction: Transcriptomes of the tumor-adjacent normal tissues are more informative than tumors in predicting recurrence in colorectal cancer patients.
J Transl Med
; 21(1): 304, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37147655
17.
A network diffusion approach to inferring sample-specific function reveals functional changes associated with breast cancer.
PLoS Comput Biol
; 13(11): e1005793, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190299
18.
High-Throughput Identification of Cis-Regulatory Rewiring Events in Yeast.
Mol Biol Evol
; 32(12): 3047-63, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26399482
19.
Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer.
BMC Cancer
; 16: 88, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26868017
20.
Regulated CRISPR Modules Exploit a Dual Defense Strategy of Restriction and Abortive Infection in a Model of Prokaryote-Phage Coevolution.
PLoS Comput Biol
; 11(11): e1004603, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26544847